Title : Stability Is Not Everything: The Case of the Cyclisation of a Thrombin-Binding Aptamer.

Pub. Date : 2019 Jul 15

PMID : 30860635






1 Functional Relationships(s)
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1 With the aim of developing a new approach to obtain improved aptamers, a cyclic thrombin-binding aptamer (TBA) analogue (cycTBA) has been prepared by exploiting a copper(I)-assisted azide-alkyne cycloaddition. Azides coagulation factor II, thrombin Homo sapiens