Pub. Date : 2019
PMID : 30858760
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Epigallocatechin-3-gallate inhibits the growth and increases the apoptosis of human thyroid carcinoma cells through suppression of EGFR/RAS/RAF/MEK/ERK signaling pathway. | epigallocatechin gallate | epidermal growth factor receptor | Homo sapiens |
2 | EGCG reduced the protein levels of phospho (p)-epidermal growth factor receptor (EGFR), H-RAS, p-RAF, p-MEK1/2, and p-extracellular signal-regulated protein kinase 1/2 (ERK1/2) in human thyroid carcinoma cells. | epigallocatechin gallate | epidermal growth factor receptor | Homo sapiens |
3 | EGCG reduced the protein levels of phospho (p)-epidermal growth factor receptor (EGFR), H-RAS, p-RAF, p-MEK1/2, and p-extracellular signal-regulated protein kinase 1/2 (ERK1/2) in human thyroid carcinoma cells. | epigallocatechin gallate | epidermal growth factor receptor | Homo sapiens |
4 | Conclusions: EGCG could reduce the growth and increase the apoptosis of human thyroid carcinoma cells through suppressing the EGFR/RAS/RAF/MEK/ERK signaling pathway. | epigallocatechin gallate | epidermal growth factor receptor | Homo sapiens |