Title : Metformin-activated AMPK regulates β-catenin to reduce cell proliferation in colon carcinoma RKO cells.

Pub. Date : 2019 Mar

PMID : 30854043






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 The decrease in beta-catenin expression was inhibited by proteosome inhibition through phosphorylation of beta-catenin at serine 33/37. Serine catenin beta 1 Homo sapiens
2 The decrease in beta-catenin expression was inhibited by proteosome inhibition through phosphorylation of beta-catenin at serine 33/37. Serine catenin beta 1 Homo sapiens
3 Given that nuclear translocation-associated phosphorylation of beta-catenin at serine was maintained, the association of beta-catenin with AMPK may sequester beta-catenin in the cytoplasm and lead to proteosomal degradation. Serine catenin beta 1 Homo sapiens