Pub. Date : 2019 Mar
PMID : 30839512
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Phenylephrine Attenuated Sepsis-Induced Cardiac Inflammation and Mitochondrial Injury Through an Effect on the PI3K/Akt Signaling Pathway. | Phenylephrine | AKT serine/threonine kinase 1 | Rattus norvegicus |
| 2 | OBJECTIVE: To investigate whether phenylephrine (PE) inhibits sepsis-induced cardiac dysfunction, cardiac inflammation, and mitochondrial injury through the PI3K/Akt signaling pathway. | Phenylephrine | AKT serine/threonine kinase 1 | Rattus norvegicus |
| 3 | OBJECTIVE: To investigate whether phenylephrine (PE) inhibits sepsis-induced cardiac dysfunction, cardiac inflammation, and mitochondrial injury through the PI3K/Akt signaling pathway. | Phenylephrine | AKT serine/threonine kinase 1 | Rattus norvegicus |
| 4 | On the other hand, PE activated the PI3K/Akt signaling pathway in the cecal ligation and puncture-treated rats, and all the protective effects of PE were abolished by wortmannin. | Phenylephrine | AKT serine/threonine kinase 1 | Rattus norvegicus |
| 5 | On the other hand, PE activated the PI3K/Akt signaling pathway in the cecal ligation and puncture-treated rats, and all the protective effects of PE were abolished by wortmannin. | Phenylephrine | AKT serine/threonine kinase 1 | Rattus norvegicus |
| 6 | CONCLUSIONS: PE attenuated sepsis-induced cardiac dysfunction, cardiac inflammation, and mitochondrial injury through the PI3K/Akt signaling pathway. | Phenylephrine | AKT serine/threonine kinase 1 | Rattus norvegicus |