Title : Cinobufagin suppresses colorectal cancer angiogenesis by disrupting the endothelial mammalian target of rapamycin/hypoxia-inducible factor 1α axis.

Pub. Date : 2019 May

PMID : 30839155






2 Functional Relationships(s)
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1 Cinobufagin suppresses colorectal cancer angiogenesis by disrupting the endothelial mammalian target of rapamycin/hypoxia-inducible factor 1alpha axis. cinobufagin mechanistic target of rapamycin kinase Homo sapiens
2 In conclusion, cinobufagin suppresses tumor neovascularization by disrupting the endothelial mTOR/HIF-1alpha pathway to trigger ROS-mediated vascular endothelial cell apoptosis. cinobufagin mechanistic target of rapamycin kinase Homo sapiens