Pub. Date : 2019 Mar 4
PMID : 30830452
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Notably, levels of most metabolites involved in amino acid metabolism and nucleotide metabolism were accumulated in oleate-treated macrophages, and these effects were alleviated or abolished by PPARA/G activation. | Oleic Acid | peroxisome proliferator activated receptor alpha | Homo sapiens |
| 2 | Additionally, during oleate-induced lipid accumulation and lipid lowering with WY-14643 and pioglitazone in macrophages, levels of most amino acids were positively associated with neutral lipid, total cholesterol, cholesterol ester, total free fatty acid and triglyceride levels but negatively associated with expression of genes related to PPARA/G signaling. | Oleic Acid | peroxisome proliferator activated receptor alpha | Homo sapiens |
| 3 | Furthermore, glycine was found to be a potential biomarker for assessing lipid accumulation and the lipid-lowering effects of PPARA/G in oleate-treated macrophages. | Oleic Acid | peroxisome proliferator activated receptor alpha | Homo sapiens |