Title : Calcitonin action on ATP citrate lyase activity in the hepatic cytosol of fed rats and its calcium-calmodulin dependency.

Pub. Date : 1986 Jan

PMID : 3081414






3 Functional Relationships(s)
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1 Administration of CT (synthetic [Asu107] eel CT; 80 MRC mU/100 g body weight) produced significant increases in ATP citrate lyase activity and calcium content in the hepatic cytosol of intact and thyroparathyroidectomized rats. Calcium calcitonin-related polypeptide alpha Rattus norvegicus
2 Administration of CT (synthetic [Asu107] eel CT; 80 MRC mU/100 g body weight) produced significant increases in ATP citrate lyase activity and calcium content in the hepatic cytosol of intact and thyroparathyroidectomized rats. Calcium calcitonin-related polypeptide alpha Rattus norvegicus
3 These results suggest that CT increases ATP citrate lyase activity in the hepatic cytosol of fed rats, and that this hormonal regulation may depend on calmodulin, and be mediated through raised calcium in the cytosol. Calcium calcitonin-related polypeptide alpha Rattus norvegicus