Title : Blocking Triggering Receptor Expressed on Myeloid Cells-1-Positive Tumor-Associated Macrophages Induced by Hypoxia Reverses Immunosuppression and Anti-Programmed Cell Death Ligand 1 Resistance in Liver Cancer.

Pub. Date : 2019 Jul

PMID : 30810243






1 Functional Relationships(s)
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Protein Name
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1 Mechanistically, TREM-1+ TAMs elevated chemokine (C-C motif) ligand 20 expression through the extracellular signal-regulated kinase/NF-kappabeta pathway in response to hypoxia and tumor metabolites leading to CCR6+ Foxp3+ Treg accumulation. tams nuclear factor kappa B subunit 1 Homo sapiens