Pub. Date : 2019 Jan
PMID : 30803422
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Metformin diminishes the unfavourable impact of Nrf2 in breast cancer patients with type 2 diabetes. | Metformin | NFE2 like bZIP transcription factor 2 | Homo sapiens |
| 2 | In previous studies, the widely used diabetes drug metformin has appeared to have a critical role in the regulation of Nrf2 function. | Metformin | NFE2 like bZIP transcription factor 2 | Homo sapiens |
| 3 | We found that high-level cytoplasmic Nrf2 expression predicted dismal overall survival and breast cancer-specific survival, but only in the patients who were not taking metformin at the time of diagnosis. | Metformin | NFE2 like bZIP transcription factor 2 | Homo sapiens |