Title : Conformational Changes in the Cytoplasmic Region of KIR3DL1 upon Interaction with SHP-2.

Pub. Date : 2019 Apr 2

PMID : 30773397






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Furthermore, individual SH2 domains of SHP-2 strongly engage with the unphosphorylated N-ITIM of 3DL1-cyto, while binding of the tandem SHP-2 SH2 domains to the bis-phosphorylated ITIMs results in more extensive conformational changes in segments I and III. Nitrogen protein tyrosine phosphatase non-receptor type 11 Homo sapiens