Title : A Platform of Synthetic Lethal Gene Interaction Networks Reveals that the GNAQ Uveal Melanoma Oncogene Controls the Hippo Pathway through FAK.

Pub. Date : 2019 Mar 18

PMID : 30773340






1 Functional Relationships(s)
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1 Dissection of the underlying mechanism revealed that FAK regulates YAP by tyrosine phosphorylation of MOB1, inhibiting core Hippo signaling. Tyrosine protein tyrosine kinase 2 Homo sapiens