Pub. Date : 2019 Apr
PMID : 30746607
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Curcumin Alleviates beta Amyloid-Induced Neurotoxicity in HT22 Cells via Upregulating SOD2. | Curcumin | superoxide dismutase 2, mitochondrial | Mus musculus |
| 2 | The aim of this study is to determine whether the type 2 superoxide dismutase (SOD2) mediates curcumin-induced protective effects in Abeta-treated neuronal cells. | Curcumin | superoxide dismutase 2, mitochondrial | Mus musculus |
| 3 | Downregulating SOD2 by using small interfering RNA (siRNA), however, significantly abolished the curcumin-induced protective and anti-oxidative effects in HT22 cells (P < 0.05); the scramble (SC)-siRNA did not cause marked effects on the curcumin-induced protective effects (P > 0.05). | Curcumin | superoxide dismutase 2, mitochondrial | Mus musculus |
| 4 | Downregulating SOD2 by using small interfering RNA (siRNA), however, significantly abolished the curcumin-induced protective and anti-oxidative effects in HT22 cells (P < 0.05); the scramble (SC)-siRNA did not cause marked effects on the curcumin-induced protective effects (P > 0.05). | Curcumin | superoxide dismutase 2, mitochondrial | Mus musculus |