Pub. Date : 2019 May
PMID : 30730256
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Involvement of ERK1/2-mediated ELK1/CHOP/DR5 pathway in 6-(methylsulfinyl)hexyl isothiocyanate-induced apoptosis of colorectal cancer cells. | 6-(Methylsulfinyl)hexyl isothiocyanate | TNF receptor superfamily member 10b | Homo sapiens |
| 2 | 6-MSITC stimulated ERK1/2 phosphorylation, and then activated ERK1/2 signaling including ELK1 phosphorylation, and upregulation of C/EBP homologous protein (CHOP) and death receptor 5 (DR5). | 6-(Methylsulfinyl)hexyl isothiocyanate | TNF receptor superfamily member 10b | Homo sapiens |
| 3 | 6-MSITC stimulated ERK1/2 phosphorylation, and then activated ERK1/2 signaling including ELK1 phosphorylation, and upregulation of C/EBP homologous protein (CHOP) and death receptor 5 (DR5). | 6-(Methylsulfinyl)hexyl isothiocyanate | TNF receptor superfamily member 10b | Homo sapiens |
| 4 | These results indicated that ERK1/2-mediated ELK1/CHOP/DR5 pathway is involved in 6-MSITC-induced apoptosis in colorectal cancer cells. | 6-(Methylsulfinyl)hexyl isothiocyanate | TNF receptor superfamily member 10b | Homo sapiens |