Title : Tissue-type plasminogen activator regulates p35-mediated Cdk5 activation in the postsynaptic terminal.

Pub. Date : 2019 Feb 28

PMID : 30709918






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1 Furthermore, our data indicate that tPA-induced p35-mediated Cdk5 activation does not induce cell death, but instead prevents NMDA-induced ubiquitylation of postsynaptic density protein-95 (PSD-95; also known as Dlg4) and the removal of GluR1 (also known as Gria1)-containing alpha-amino-3-hydroxy-5-methyl-4-isoxazoleproprionic acid (AMPA) receptors from the PSD. N-Methylaspartate cyclin dependent kinase 5 Homo sapiens