Title : Modern view on the place of riociguat in the treatment of pulmonary hypertension.

Pub. Date : 2018 Apr 19

PMID : 30701875






1 Functional Relationships(s)
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1 Until recently, the only therapeutic strategy to influence the molecular pathway of nitric oxide (NO) - soluble guanylate cyclase (sGC) - cyclic guanosine monophosphate (cGMP) was the use of phosphodiesterase type 5 inhibitors (PDE-5 inhibitors), such as sildenafil. Nitric Oxide phosphodiesterase 5A Homo sapiens