Title : Anti-inflammatory property of quercetin through downregulation of ICAM-1 and MMP-9 in TNF-α-activated retinal pigment epithelial cells.

Pub. Date : 2019 Apr

PMID : 30685603






2 Functional Relationships(s)
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1 Quercetin inhibited the TNF-alpha-induced phosphorylation of PKCdelta, JNK1/2, ERK1/2. Quercetin mitogen-activated protein kinase 3 Homo sapiens
2 These results suggest that quercetin attenuates TNF-alpha-induced ICAM-1 and MMP-9 expression in ARPE-19 cells via the MEK1/2-ERK1/2 and PKCdelta-JNK1/2-c-Jun or NF-kappaB pathways. Quercetin mitogen-activated protein kinase 3 Homo sapiens