Title : MicroRNA-125b-5p improves pancreatic β-cell function through inhibiting JNK signaling pathway by targeting DACT1 in mice with type 2 diabetes mellitus.

Pub. Date : 2019 May 1

PMID : 30684546






2 Functional Relationships(s)
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1 miR-125b-5p inhibited DACT1 expression and the activation of the JNK signaling pathway, as well as restrained cell proliferation and promoted cell apoptosis. mir-125b-5p mitogen-activated protein kinase 8 Mus musculus
2 The current results suggest that up-regulated miR-125b-5p promotes insulin sensitivity and enhances pancreatic beta-cell function through inhibiting the JNK signaling pathway by negatively mediating DACT1. mir-125b-5p mitogen-activated protein kinase 8 Mus musculus