Title : Post-infarct morphine treatment mitigates left ventricular remodeling and dysfunction in a rat model of ischemia-reperfusion.

Pub. Date : 2019 Mar 15

PMID : 30684466






2 Functional Relationships(s)
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1 Five-day morphine administration markedly improved LV function, and also reduced infarct size, myocyte hypertrophy, fibrosis, index of infarct expansion, heart weight and serum TNF-alpha level. Morphine tumor necrosis factor Rattus norvegicus
2 Morphine also altered the mRNA expression of fibrosis-related genes, TNF-alpha, MMP-2 and MMP-9. Morphine tumor necrosis factor Rattus norvegicus