Title : Off-target based drug repurposing opportunities for tivantinib in acute myeloid leukemia.

Pub. Date : 2019 Jan 24

PMID : 30679640






1 Functional Relationships(s)
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1 Tivantinib alone, or in combination with ABT-199, downregulated anti-apoptotic MCL-1 and BCL-XL levels, which likely contribute to the observed synergy. 2,2'-azino-di-(3-ethylbenzothiazoline)-6-sulfonic acid MCL1 apoptosis regulator, BCL2 family member Homo sapiens