Title : Screening Pyridine Derivatives against Human Hydrogen Sulfide-synthesizing Enzymes by Orthogonal Methods.

Pub. Date : 2019 Jan 24

PMID : 30679627






1 Functional Relationships(s)
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1 Here, the human enzymes CBS, CSE and MST were expressed and purified from Escherichia coli, and thirty-one pyridine derivatives were synthesized and screened for their ability to bind and inhibit these enzymes. pyridine cystathionine beta-synthase Homo sapiens