Title : Canonical Wnt is inhibited by targeting one-carbon metabolism through methotrexate or methionine deprivation.

Pub. Date : 2019 Feb 19

PMID : 30679275






2 Functional Relationships(s)
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Compound Name
Protein Name
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1 Our recent work uncovered a requirement for cytoplasmic arginine methylation during Wnt signaling through the activity of protein arginine methyltransferase 1 (PRMT1), which transfers one-carbon groups from SAM to many protein substrates. Arginine protein arginine methyltransferase 1 Homo sapiens
2 Our recent work uncovered a requirement for cytoplasmic arginine methylation during Wnt signaling through the activity of protein arginine methyltransferase 1 (PRMT1), which transfers one-carbon groups from SAM to many protein substrates. Arginine protein arginine methyltransferase 1 Homo sapiens