Title : Antihypertensive Potential of Coenzyme Q10 via Free Radical Scavenging and Enhanced Akt-nNOS Signaling in the Nucleus Tractus Solitarii in Rats.

Pub. Date : 2019 Mar

PMID : 30668894






2 Functional Relationships(s)
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1 Oral CoQ10 reduced blood pressure by inducing Akt and nNOS phosphorylation in NTS of fructose-induced hypertensive rats. coenzyme Q10 nitric oxide synthase 1 Rattus norvegicus
2 CONCLUSION: Oral CoQ10 decreases blood pressure by negatively regulating fructose-induced NADPH oxidase levels, abolishing ROS generation, reducing p38 phosphorylation, and enhancing the Akt-nNOS pathway in the NTS. coenzyme Q10 nitric oxide synthase 1 Rattus norvegicus