Title : A JAK1 Selective Kinase Inhibitor and Tofacitinib Affect Macrophage Activation and Function.

Pub. Date : 2019 Mar 14

PMID : 30668755






1 Functional Relationships(s)
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1 CONCLUSION: JAK1i and tofacitinib but not JAK3i induce phenotypical and functional characteristics of anti-inflammatory macrophages, suggesting JAK1 as the main effector pathway for tofacitinib in these cells. tofacitinib Janus kinase 1 Mus musculus