Title : A genetic deletion of the serotonin transporter differentially influences the behavioural effects of MDMA.

Pub. Date : 2019 Mar

PMID : 30665313






3 Functional Relationships(s)
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1 A genetic deletion of the serotonin transporter differentially influences the behavioural effects of MDMA. N-Methyl-3,4-methylenedioxyamphetamine solute carrier family 6 member 4 Rattus norvegicus
2 When the acquirers were challenged with AMPH, SERT+/+ showed partial, while SERT-/- rats showed full generalisation to MDMA. N-Methyl-3,4-methylenedioxyamphetamine solute carrier family 6 member 4 Rattus norvegicus
3 In the ASR paradigm, MDMA significantly reduced prepulse inhibition and startle habituation in SERT+/+ rats, while having no effect in SERT-/- rats. N-Methyl-3,4-methylenedioxyamphetamine solute carrier family 6 member 4 Rattus norvegicus