Title : Structural insights into the tyrosine phosphorylation-mediated inhibition of SH3 domain-ligand interactions.

Pub. Date : 2019 Mar 22

PMID : 30659095






1 Functional Relationships(s)
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1 Here, we present the first crystal structures of tyrosine-phosphorylated human SH3 domains derived from the Abelson-family kinases ABL1 and ABL2 at 1.6 and 1.4 A resolutions, respectively. Tyrosine ABL proto-oncogene 1, non-receptor tyrosine kinase Homo sapiens