Title : Th1 cytokines sensitize HER-expressing breast cancer cells to lapatinib.

Pub. Date : 2019

PMID : 30657766






2 Functional Relationships(s)
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Compound Name
Protein Name
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1 The targeted anti-cancer agent, lapatinib, is a small molecule inhibitor that directly interferes with EGFR (HER-1)and HER-2 signaling, and indirectly reduces HER-3 signaling, thus suppressing important downstream events. Lapatinib epidermal growth factor receptor Homo sapiens
2 The targeted anti-cancer agent, lapatinib, is a small molecule inhibitor that directly interferes with EGFR (HER-1)and HER-2 signaling, and indirectly reduces HER-3 signaling, thus suppressing important downstream events. Lapatinib epidermal growth factor receptor Homo sapiens