Title : Construction of Dual Stimuli-Responsive Platinum(IV) Hybrids with NQO1 Targeting Ability and Overcoming Cisplatin Resistance.

Pub. Date : 2019 Feb 4

PMID : 30657321






1 Functional Relationships(s)
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1 The mechanism studies showed that the hybrids could be activated by both NQO1 and ascorbic acid to release the cytotoxic Pt(II) unit, exhibiting a dual stimuli-responsive character. pt(ii) NAD(P)H dehydrogenase, quinone 1 Mus musculus