| Protein Name | NAD(P)H dehydrogenase, quinone 1 |
|---|---|
| Organism | Mus musculus |
| Gene ID | 18104 |
| Gene Symbol | Nqo1 |
| UniProt | Q64669 (NQO1_MOUSE), Q542Y0 (Q542Y0_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
530
Total Number of Articles : 591 |
Description |
NAD(P)H dehydrogenase, quinone 1 |
| Gene Summary |
Enables NADH dehydrogenase (quinone) (non-electrogenic) activity. Involved in several processes, including protein polyubiquitination; response to lipopolysaccharide; and vitamin K metabolic process. Acts upstream of or within negative regulation of catalytic activity; response to caloric restriction; and response to oxidative stress. Is active in cytoplasm and nucleus. Is expressed in heart; liver; main olfactory bulb; olfactory epithelium; and skin. Human ortholog(s) of this gene implicated in several diseases, including hematologic cancer (multiple); hypertension; lung disease (multiple); macular degeneration; and small cell carcinoma. Orthologous to human NQO1 (NAD(P)H quinone dehydrogenase 1). [provided by Alliance of Genome Resources, Jun 2025] |
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