Title : Enhanced Macrophage Pannexin 1 Expression and Hemichannel Activation Exacerbates Lethal Experimental Sepsis.

Pub. Date : 2019 Jan 17

PMID : 30655582






2 Functional Relationships(s)
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1 We have recently reported an important role of Connexin 43 (Cx43) hemichannels in the pathogenesis of lethal sepsis through facilitating ATP efflux to potentiate the double-stranded RNA-activated protein kinase R (PKR)-dependent macrophage activation. Adenosine Triphosphate gap junction protein alpha 1 Homo sapiens
2 We have recently reported an important role of Connexin 43 (Cx43) hemichannels in the pathogenesis of lethal sepsis through facilitating ATP efflux to potentiate the double-stranded RNA-activated protein kinase R (PKR)-dependent macrophage activation. Adenosine Triphosphate gap junction protein alpha 1 Homo sapiens