Title : Computational Studies of bis-2-Oxoindoline Succinohydrazides and their In Vitro Cytotoxicity.

Pub. Date : 2020

PMID : 30652647






1 Functional Relationships(s)
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1 Molecular docking studies on EGFR (PDB ID: 1M17) results, the compounds 6d, 6j and 6l showed good dock/PLP scores i.e.-81.28, -73.98 and -75.37 by interacting with Leu-694, Val-702and Gly-772 amino acids via hydrophobic and hydrogen bonds with Asn818 and Met-769. Hydrogen epidermal growth factor receptor Homo sapiens