Title : Uric acid activates aldose reductase and the polyol pathway for endogenous fructose and fat production causing development of fatty liver in rats.

Pub. Date : 2019 Mar 15

PMID : 30651350






2 Functional Relationships(s)
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1 These results suggest that uric acid generated during fructose metabolism may act as a positive feedback mechanism that stimulates endogenous fructose production by stimulating aldose reductase in the polyol pathway. Fructose aldo-keto reductase family 1 member B1 Rattus norvegicus
2 These results suggest that uric acid generated during fructose metabolism may act as a positive feedback mechanism that stimulates endogenous fructose production by stimulating aldose reductase in the polyol pathway. Fructose aldo-keto reductase family 1 member B1 Rattus norvegicus