Title : Metformin counteracts glucose-dependent lipogenesis and impairs transdeamination in the liver of gilthead sea bream ( Sparus aurata).

Pub. Date : 2019 Mar 1

PMID : 30649892






1 Functional Relationships(s)
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1 Metformin counteracted glucose-dependent effects, and downregulated glutamate dehydrogenase, alanine aminotransferase, and mammalian target of rapamycin 5 h posttreatment in the absence of a glucose load, leading to decreased long-term activity of PFK1 and IDH. Metformin glutamic--pyruvic transaminase Homo sapiens