Title : Superior efficacy of cotreatment with BET protein inhibitor and BCL2 or MCL1 inhibitor against AML blast progenitor cells.

Pub. Date : 2019 Jan 15

PMID : 30647404






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Venetoclax and A-1210477 bind and inhibit the antiapoptotic activity of BCL2 and MCL1, respectively, lowering the threshold for apoptosis. A-1210477 MCL1 apoptosis regulator, BCL2 family member Homo sapiens