Title : Anti-tumor macrophages activated by ferumoxytol combined or surface-functionalized with the TLR3 agonist poly (I : C) promote melanoma regression.

Pub. Date : 2018

PMID : 30613299






1 Functional Relationships(s)
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1 However, FMT combined with PIC synergistically inhibited their proliferation by shifting macrophages to a tumoricidal phenotype with upregulated TNF-alpha and iNOS, increased NO secretion and augmented phagocytosis induced by NOX2-derived ROS in vitro. Poly I-C nitric oxide synthase 2, inducible Mus musculus