Pub. Date : 2018 Dec 23
PMID : 30582209
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Through the detection of protein expression, EGCG was observed to possess the ability to downregulate the accumulation of AGE-RAGE in pancreatic tissues as well as in the transcription factor nuclear factor-kappaB (NF-kappaB), which represents a potentially significant method by which EGCG influences diabetes. | epigallocatechin gallate | nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 | Mus musculus |
| 2 | Through the detection of protein expression, EGCG was observed to possess the ability to downregulate the accumulation of AGE-RAGE in pancreatic tissues as well as in the transcription factor nuclear factor-kappaB (NF-kappaB), which represents a potentially significant method by which EGCG influences diabetes. | epigallocatechin gallate | nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 | Mus musculus |
| 3 | Through the detection of protein expression, EGCG was observed to possess the ability to downregulate the accumulation of AGE-RAGE in pancreatic tissues as well as in the transcription factor nuclear factor-kappaB (NF-kappaB), which represents a potentially significant method by which EGCG influences diabetes. | epigallocatechin gallate | nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 | Mus musculus |
| 4 | Through the detection of protein expression, EGCG was observed to possess the ability to downregulate the accumulation of AGE-RAGE in pancreatic tissues as well as in the transcription factor nuclear factor-kappaB (NF-kappaB), which represents a potentially significant method by which EGCG influences diabetes. | epigallocatechin gallate | nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 | Mus musculus |
| 5 | The results of this study provided evidence indicating that EGCG can effectively improve the morphology of pancreatic tissues, but notably reduce blood glucose levels in diabetic mice, which may be related to its inhibition of AGE-RAGE signaling pathway and activation of transcription factor NF-kappaB pathway. | epigallocatechin gallate | nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 | Mus musculus |