Title : Schedule-dependent synergistic effects of 5-fluorouracil and selumetinib in KRAS or BRAF mutant colon cancer models.

Pub. Date : 2019 Feb

PMID : 30579838






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1 Schedule-dependent synergistic effects of 5-fluorouracil and selumetinib in KRAS or BRAF mutant colon cancer models. AZD 6244 KRAS proto-oncogene, GTPase Homo sapiens
2 Our results suggest that sequential administration of 5-FU plus selumetinib would be a promising strategy for patients having KRAS or BRAF mutant colon cancers. AZD 6244 KRAS proto-oncogene, GTPase Homo sapiens