Title : Insulin PACS a Punch in SIRT1 Activity.

Pub. Date : 2018 Dec 20

PMID : 30576653






1 Functional Relationships(s)
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1 (2018) describe a mechanism by which insulin signaling represses the NAD+-dependent SIRT1 deacetylase by promoting PACS-2 binding and provide structural clues to understanding how SIRT1 activating compounds (STACs) work. NAD insulin Homo sapiens