Title : ZNF300 stimulates fatty acid oxidation and alleviates hepatosteatosis through regulating PPARα.

Pub. Date : 2019 Jan 31

PMID : 30568000






2 Functional Relationships(s)
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1 Investigations of the underlying mechanisms revealed that ZNF300 directly binds to and regulates the PPARalpha expression, thus promoting fatty acid oxidation. Fatty Acids peroxisome proliferator activated receptor alpha Homo sapiens
2 These results suggested that ZNF300 plays an important role in hepatic lipid metabolism via PPARalpha promoting fatty acid oxidation and this effect might be blocked by DNMT3a-mediated methylation of ZNF300. Fatty Acids peroxisome proliferator activated receptor alpha Homo sapiens