Pub. Date : 2019 Feb
PMID : 30565854
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Rosuvastatin use reduces thrombin generation potential in patients with venous thromboembolism: a randomized controlled trial. | Rosuvastatin Calcium | coagulation factor II, thrombin | Homo sapiens |
| 2 | Endogenous thrombin potential and peak were decreased by 10% and 5% with rosuvastatin therapy. | Rosuvastatin Calcium | coagulation factor II, thrombin | Homo sapiens |
| 3 | Endogenous thrombin potential (ETP) increased from baseline to end of study in non-statin users (mean 97.22 nm*min; 95% CI, 40.92-153.53) and decreased in rosuvastatin users (mean -24.94 nm*min; 95% CI, -71.81 to 21.93). | Rosuvastatin Calcium | coagulation factor II, thrombin | Homo sapiens |
| 4 | The thrombin peak increased in both non-statin (mean 20.69 nm; 95% CI, 9.80-31.58) and rosuvastatin users (mean 8.41 nm; 95% CI -0.86 to 17.69). | Rosuvastatin Calcium | coagulation factor II, thrombin | Homo sapiens |
| 5 | We conclude that rosuvastatin reduces thrombin generation potential in patients who had VTE. | Rosuvastatin Calcium | coagulation factor II, thrombin | Homo sapiens |