Title : Inhibition of Lung Cancer by 2-Methoxy-6-Acetyl-7-Methyljuglone Through Induction of Necroptosis by Targeting Receptor-Interacting Protein 1.

Pub. Date : 2019 Jul 10

PMID : 30556404






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 A positive feedback loop between calcium (Ca2+) and c-Jun N-terminal kinase (JNK) occurred following ROS generation, leading to lysosomal membrane permeabilization and mitochondrial dysfunction. Calcium mitogen-activated protein kinase 8 Homo sapiens
2 A positive feedback loop between calcium (Ca2+) and c-Jun N-terminal kinase (JNK) occurred following ROS generation, leading to lysosomal membrane permeabilization and mitochondrial dysfunction. Calcium mitogen-activated protein kinase 8 Homo sapiens