Title : New therapeutic strategy of hinokitiol in haemorrhagic shock-induced liver injury.

Pub. Date : 2019 Mar

PMID : 30548082






3 Functional Relationships(s)
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1 Hinokitiol could inhibited NF-kappaB activation and IL-6 and TNF-alpha upregulation in liver tissues. beta-thujaplicin nuclear factor kappa B subunit 1 Homo sapiens
2 Moreover, hinokitiol attenuated H/R-stimulated NF-kappaB activation and reduced the levels of IL-6 and TNF-alpha mRNAs, suggesting that hinokitiol can protect hepatocytes from H/R injury. beta-thujaplicin nuclear factor kappa B subunit 1 Homo sapiens
3 Collectively, our data suggest that hinokitiol attenuates liver injury following HS/R, partly through the inhibition of NF-kappaB activation. beta-thujaplicin nuclear factor kappa B subunit 1 Homo sapiens