Title : Neuroprotective effect of Notch pathway inhibitor DAPT against focal cerebral ischemia/reperfusion 3 hours before model establishment.

Pub. Date : 2019 Mar

PMID : 30539813






1 Functional Relationships(s)
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1 DAPT decreased the number of glial fibrillary acidic protein- and Notch1-positive cells in the right prefrontal cortex, while also reducing the number of apoptotic cells and decreasing interleukin-6 and tumor necrosis factor-alpha contents, and simultaneously downregulating Hes1 and Hes5 protein expression. dapt interleukin 6 Mus musculus