Title : Orexin-A Exerts Neuroprotective Effects via OX1R in Parkinson's Disease.

Pub. Date : 2018

PMID : 30524223






1 Functional Relationships(s)
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1 The results from animal experiments demonstrated that orexin-A attenuated the loss of dopaminergic neurons and the decrease of tyrosine hydroxylase (TH) expression in the substantia nigra, normalized the striatal dopaminergic fibers, and prevented the depletion of dopamine and its metabolites in the striatum. Dopamine hypocretin Mus musculus