Pub. Date : 2018
PMID : 30498565
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Two weeks of dietary restriction of the serotonin precursor tryptophan ameliorated both brain hyperserotonemia and ASD-relevant social deficits in Sert HZ and KO mice. | Tryptophan | solute carrier family 6 (neurotransmitter transporter, serotonin), member 4 | Mus musculus |
| 2 | The expression of rather distinct sets of genes was altered in Sert HZ and KO mice, and a substantial portion of these genes was also affected by tryptophan depletion. | Tryptophan | solute carrier family 6 (neurotransmitter transporter, serotonin), member 4 | Mus musculus |
| 3 | Tryptophan depletion in Sert HZ and KO mice was associated with alterations in the expression of genes involved in signal transduction pathways initiated by changes in extracellular serotonin or melatonin, a derivative of serotonin. | Tryptophan | solute carrier family 6 (neurotransmitter transporter, serotonin), member 4 | Mus musculus |