Protein Name | solute carrier family 6 (neurotransmitter transporter, serotonin), member 4 |
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Organism | Mus musculus |
Gene ID | 15567 |
Gene Symbol | Slc6a4 |
UniProt | Q60857 (SC6A4_MOUSE) |
Relationships |
Total Number of functionally related compound(s) :
206
Total Number of Articles : 302 |
Description |
solute carrier family 6 (neurotransmitter transporter, serotonin), member 4 |
Gene Summary |
Enables neurotransmitter transmembrane transporter activity; nitric-oxide synthase binding activity; and serotonin:sodium:chloride symporter activity. Involved in several processes, including nervous system development; platelet aggregation; and serotonin uptake. Located in focal adhesion and synapse. Is expressed in several structures, including early conceptus; heart; liver; nervous system; and ovary. Used to study autism spectrum disorder and sudden infant death syndrome. Human ortholog(s) of this gene implicated in several diseases, including alcohol dependence; anxiety disorder (multiple); depressive disorder (multiple); heart disease (multiple); and substance abuse (multiple). Orthologous to human SLC6A4 (solute carrier family 6 member 4). [provided by Alliance of Genome Resources, Jun 2025] |
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