Title : Ameliorating effects of bortezomib, a proteasome inhibitor, on development of dextran sulfate sodium-induced murine colitis.

Pub. Date : 2018 Nov

PMID : 30487672






1 Functional Relationships(s)
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1 In HT-29 cells, bortezomib blocked tumor necrosis factor-alpha (TNF-alpha)-induced nuclear translocation of NF-kappaB and this was accompanied by an increase in ubiquitinated IkappaBalpha in the cytoplasm. Bortezomib NFKB inhibitor alpha Homo sapiens