Title : Sirtuin 2-mediated deacetylation of cyclin-dependent kinase 9 promotes STAT1 signaling in type I interferon responses.

Pub. Date : 2019 Jan 18

PMID : 30487288






1 Functional Relationships(s)
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1 We found that SIRT2 deacetylates cyclin-dependent kinase 9 (CDK9) in a type I IFN-dependent manner and that the CDK9 deacetylation is essential for STAT1 phosphorylation at Ser-727. Serine sirtuin 2 Mus musculus