Pub. Date : 2018 Nov
PMID : 30486739
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | This work was undertaken to evaluate the expression of B7-H3 and B7-H4 in phyllodes tumors and assess the association with the grade and clinical behavior of phyllodes tumors. | phyllodes | CD276 antigen | Mus musculus |
| 2 | B7-H3 messenger RNA and protein appeared to be concentrated mainly in the stromal compartment of phyllodes tumors. | phyllodes | CD276 antigen | Mus musculus |
| 3 | Stromal B7-H3 messenger RNA and protein expression were noted in 10 (16.7%) and 31 (51.7%) of 60 benign phyllodes tumors, 12 (46.1%) and 20 (76.9%) of 26 borderline phyllodes tumors, and 10 (66.7%) and 13 (86.7%) of 15 malignant phyllodes tumors, respectively. | phyllodes | CD276 antigen | Mus musculus |
| 4 | Stromal B7-H3 messenger RNA and protein expression were noted in 10 (16.7%) and 31 (51.7%) of 60 benign phyllodes tumors, 12 (46.1%) and 20 (76.9%) of 26 borderline phyllodes tumors, and 10 (66.7%) and 13 (86.7%) of 15 malignant phyllodes tumors, respectively. | phyllodes | CD276 antigen | Mus musculus |
| 5 | Stromal B7-H3 messenger RNA and protein expression were noted in 10 (16.7%) and 31 (51.7%) of 60 benign phyllodes tumors, 12 (46.1%) and 20 (76.9%) of 26 borderline phyllodes tumors, and 10 (66.7%) and 13 (86.7%) of 15 malignant phyllodes tumors, respectively. | phyllodes | CD276 antigen | Mus musculus |
| 6 | Stromal B7-H3 messenger RNA and protein expression increased as phyllodes tumors progressed from benign to borderline and finally to the malignant grade (Pearson"s R = 0.411, p < 0.001 and Pearson"s R = 0.293, p = 0.003, respectively). | phyllodes | CD276 antigen | Mus musculus |
| 7 | These results suggest that B7-H3 is involved in the progression of phyllodes tumors and may contribute to their immune surveillance. | phyllodes | CD276 antigen | Mus musculus |