Title : The Mitochondrial Apoptotic Effectors BAX/BAK Activate Caspase-3 and -7 to Trigger NLRP3 Inflammasome and Caspase-8 Driven IL-1β Activation.

Pub. Date : 2018 Nov 27

PMID : 30485804






1 Functional Relationships(s)
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1 Furthermore, BAX/BAK signaling induces a parallel pathway to NLRP3 inflammasome-mediated caspase-1-dependent IL-1beta maturation that requires potassium efflux. Potassium NLR family pyrin domain containing 3 Homo sapiens