Title : Mitogen-activated kinase kinase kinase 1 inhibits hedgehog signaling and medulloblastoma growth through GLI1 phosphorylation.

Pub. Date : 2019 Feb

PMID : 30483764






1 Functional Relationships(s)
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1 Of note, the enforced expression of MEKK1 or the exposure of medulloblastoma cells to the MEKK1 activator, Nocodazole, resulted in a marked inhibitory effect on GLI1 activity and tumor cell proliferation and viability. Nocodazole GLI family zinc finger 1 Homo sapiens